The lesions were not significantly different between sides. Mean diameters of cryoablation ice balls on the gelatin sponge and control sides were 3.9 cm +/- 0.2 and 3.8 cm +/- 0.4, respectively.
#PORCINE GELATIN SPONGE SKIN#
Gross and histopathologic results confirmed that the gelatin sponge was in the cryoablation puncture sites. In this work, the potential of salmon skin gelatin was investigated, in a comparative study with porcine gelatin, and an enzymatic versus chemical cross-linking analysis. The use of gelatin sponge resulted in significantly less blood loss (mean, 8.24 mg +/- 4.68) compared with the control kidneys (mean, 20.24 mg +/- 8.14 P =. The kidneys treated with gelatin sponge were removed and grossly and histologically examined to identify the gelatin sponge at the puncture cryolesion. Acute blood loss was compared between the two groups. Blood loss was measured by calculating the change in weight of the sponges after 30 minutes of absorption time. Porcine gelation with hemostatic properties helps provide a matrix for platelet adhesion and aggregation Liquefy within 2 to 5 days when applied to bleeding. After removal of the sheath, a midline laparotomy incision was performed and sponges were placed around the kidneys. Retailer of Porcine Haemostatic Absorbable Gelatin Sponge - Surgispon Haemostatic Absorbable Sponge offered by Alinda Healthcare Pvt. The cryoablation location and protocol were applied identically to both kidneys in each pig however, only one side received gelatin sponge injection after cryoablation through a coaxial sheath (3 mm). SURGIFOAM® is a sterile, water-insoluble, malleable, porcine gelatin absorbable sponge or powder intended for hemostatic use by applying to a bleeding surface. This study describes the use of a porcine model to test the ability of gelatin sponge injection into the tract to limit bleeding at the site of cryoprobe puncture.Ī total of nine swine (18 kidneys) underwent bilateral ultrasound-guided PRC with double freeze/thaw cycle protocol with use of a 2.4-mm cryoprobe.
Achievement of hemostasis can be a challenge during percutaneous renal cryoablation (PRC).
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